Amitriptyline is used in the treatment of certain mood disorders and mental problems. It can help relieve low moods, anxiety, tension and cause feelings of well-being and is therefore used often to treat conditions such as depression. It can also cause a patient to have an increase in energy and helps normalise sleep patterns.

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Product Description

What is Amitriptyline?

Amitriptyline has historically been used to treat conditions such as depression and anxiety, promoting an increase in mood and a relief from associated symptoms. Amitriptyline is a tricyclic antidepressant that has also been found to be beneficial in the treatment of neuropathic pain in conditions such as fibromyalgia, chronic or tension migraines, spinal problems and arthritis.  The latest research in using low dose Amitriptyline to treat pain has produced positive results and has led to this medication fast becoming one of the most widely used treatments for this condition.  Amitriptyline is also sold under the brand name Elavil.


How Amitriptyline Works

Amitriptyline works by increasing the amount of the neurotransmitter serotonin within the brain, this transmitter is known to play a key role in the regulation of mood and can also reduce pain messages received within the brain. Chronic pain is thought to have a different mechanism of action to other forms of pain specifically within the peripheral and central nervous systems (brain and spinal cord).  Nerves can become oversensitive causing magnified pain messages to reach and be interpreted by the brain.  Amitriptyline can resolve this issue by increasing the amount of serotonin within the brain that can subsequently decrease the pain messages being received.  As Amitriptyline inhibits these messages being interpreted to the same degree the patient will feel reduced pain.


Additional Benefits of Amitriptyline

Sufferers of chronic pain are also more likely to suffer from low mood and disturbed sleep patterns, both issues that Amitriptyline can address. As a proven mood regulator due to its use in treating depression, Amitriptyline can boost a patients mood helping them to deal with any co-morbid conditions. Amitriptyline also contains sleep inducing properties and can be prescribed to treat insomnia, this can be particularly helpful for those suffering chronic pain that subsequently interferes with their ability to sleep

Amitriptyline FAQ

What are amitriptyline tablets used for?
How amitriptyline works for pain?
Which is better amitriptyline or nortriptyline?
Are amitriptyline used for migraines?
Why is amitriptyline used for nerve pain?
When should amitriptyline be taken?
What amitriptyline 10mg is used for?


The effects of pre-emptive treatment ofpostherpetic neuralgia with amitriptyline: A randomized, double-blind, placebo-controlled trial
Amitriptyline versus placebo in postherpetic neuralgia
Amitriptyline relieves diabetic neuropathy pain in patients with normal or depressed mood
A randomized, controlled trial of amitriptyline and naproxen in the treatment of patients with fibromyalgia
Amitriptyline – Johns Hopkins Medicine

Additional Information


10mg (28 Tablets), 25mg (28 Tablets)


1 Pack, 2 Packs, 3 Packs

Side Effects

If you experience blurred vision, dizziness, weight gain, dry mouth, constipation, or urination problems, it is important to inform your doctor at once.

Some of these symptoms can be avoided through altering your lifestyle. Constipation can be solved by sticking to a diet with sufficient fibre, exercise and plenty of water. Dizziness can be helped by rising slowly from lying or sitting positions.

Dry mouth can be avoided by eating sugarless ice chips or candy, chewing bubblegum, drinking plenty of water, or by utilizing a saliva substitute.

There are also far rarer side effects of using Amitriptyline. These include persistent heartburn, mask-like facial expressions, easy bruising or bleeding, shaking, severe abdominal pain, enlarged and painful breasts, muscle spasms, and decreased sex drive.

There are also more severe side effects such as seizures, vision changes, vomit that resembles coffee grounds, black stools, eye pain, eye swelling, eye redness, dizziness, and fainting.

If you have any of these side effects, alert your doctor immediately so you can receive proper medical treatment.


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