What is Duloextine
Duloxetine also known under the brand name Cymbalta has historically been used in the treatment of depression, anxiety and associated mood problems. Duloxteine belongs to a classification of drugs known as serotonin noradrenergic reuptake inhibitors or SNRI. In more recent times Duloxetine has been used to treat different types of pain including the pain resulting fromnerves, burning or shooting pain, pain associated with diabetes and for pain that interferes with the ability to sleep. Research into the benefits of Duloxetine and pain have provided promising results and has contributed to its utilisation in this field.
In 2008 the USA Food and Drug Administration approved the use of Duloxetine in the treatment of Fibromylagia, a condition that results in wide spread pain all over the body. Subsequently in 2010 the Adminstration granted approval for the use of Duloxetine to treat musculoskeletal pain that becomes chronic as experienced by those with pain in the lower back or sufferers of osteoarthritis.
How does Duloextine work
Duloextine works by increasing both serotonin and noradrenaline available within the nervous system. These neurotransmitters are believed to be involved in the processes of thinking and mood but increasing the amounts also appear to contribute to a reduction in the processing of pain messages that reach the brain. This reduction in pain messages is how duloextine contributes to the alleviation of pain felt by the patient.
Duloextine does need to be taken over a period of time to take its full effect and generally it can take around two weeks before the first noticeable changes in pain levels are noted by the patient and can take up to six weeks before it reaches its highest level of pain reduction. Therefore it is important to continue to use Duloextine for this six week period to determine whether the medication is having the appropriate effect on you before seeking further advice from your physician.